Week Ending December 13, 2021

More Seniors Need Liver Transplants, Often Due to NASH
“The proportion of older people requiring a liver transplant has greatly increased, likely due to the concurrent rise in fatty liver disease, according to findings presented at the AASLD Liver Meeting.”

Genetic Variability in Patients with HCV-Related Hepatocellular Carcinoma
“Phylogenetic trees showed that there was no difference in the virus populations in the three compartments analyzed for the three HCV regions in patients with HCC. Low variability and no difference between the Cases and Controls were observed in the core and NS5A regions; however, in the NS3 region, a higher variability was observed in the Cases.”

Multiple Barriers Prevent Better HCV Care for Homeless Population
“There are a number of reasons why individuals with lived homeless experiences are unable to receive hepatitis C virus (HCV) screenings and treatments.”

Health Care for People With NASH and Obesity Will Cost Billions
“Non-alcoholic steatohepatitis (NASH) in people with obesity will result in more deaths than NASH in the absence of obesity and will require an estimated expenditure of billions of dollars, according to findings presented at the AASLD Liver Meeting 2021.”

Interactions between RNA viruses and human RNA-binding proteins
“Class IV and class V viruses are single-stranded RNA (ssRNA viruses) in which the positive sense genome is translated into protein by host machinery, allowing viral reproduction. ssRNA class V viruses contain a negative sense genome that must be transcribed into a positive-sense strand before translation.”

Regular Thyroid Screening Recommended for People With Hepatitis C
“People with hepatitis C should be regularly screened for thyroid disorders due to an increased risk for primary and subclinical hypothyroidism. These findings, from a case-control study, were published in Cureus.”

Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study
“Hepatocellular carcinoma is a frequent consequence of alcohol-related liver disease, with variable incidence among heavy drinkers. We did a genome-wide association study (GWAS) to identify common genetic variants for alcohol-related hepatocellular carcinoma.”

Decreasing opioid deaths, not with abstinence, but harm reduction
“For close to two years now, North Carolina has been grappling with the coronavirus pandemic, but it’s not the only public health crisis plaguing the state.”

This Is Your Liver on Hep C
“THE LIVER, BY all accounts, is one of the most important organs in the human body. It literally cleans the blood by keeping the good things in and getting rid of toxins and helps your body maintain healthy glucose levels.”

Virginia Medicaid is removing its final barrier to treatment for hepatitis C
“Beginning in January, Virginia Medicaid will eliminate its final restriction to the treatment of hepatitis C — the need for providers to receive prior authorization for the medication.”