Hepatitis C News
Week Ending September 27, 2021

What is hepatitis C viral load?
“A hepatitis C viral load can indicate if people have contracted an active hepatitis C infection or whether treatment is reducing levels of the virus. A high viral load indicates high virus levels, while a low viral load indicates lower amounts. The viral load levels do not relate to other effects of hepatitis C, such as liver condition.”

Better Cirrhosis Monitoring Methods Needed for Hepatitis C Patients
“Recent study results highlight the need to develop better surveillance techniques for whether a patient who achieved a sustained virologic response following treatment for hepatitis C virus (HCV) will develop cirrhosis.”

Antiretroviral Therapy Protects Against Liver Cancer in People With Hepatitis C and HIV
“Among individuals with both hepatitis C virus (HCV) and HIV who received direct-acting antiviral therapy for HCV, the cirrhosis severity and a higher CD4 T-cell count were linked to a greater risk of developing hepatocellular carcinoma. Conversely, antiretroviral therapy for HIV lowered the risk for liver cancer, according to results published in AIDS.”

Patients with Liver Cancer and Hepatitis or HIV May Face Higher Mortality Rates
“Patients with hepatocellular carcinoma (HCC) who also have hepatitis C or hepatitis B with or without HIV may have higher mortality rates than those who are not coinfected, according to study results. This coinfected patient subset is also at higher risk for tumor diagnosis at a younger age and a higher frequency of tumoral thrombosis (when a tumor extends into a blood vessel).”

Exploring a key to hepatitis C entry into cells
“In a new paper published in Nature, scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, describe the structure of a key protein on the surface of the hepatitis C virus (HCV) and how it interacts with its receptor found on some human cells.”