Caring Ambassadors Hepatitis C Program Newsletter

www.HepCChallenge.org

September 2009

 

Clinical Trials, Cohort Studies, Pilot Studies

 

Validation of three non-invasive markers in assessing the severity of liver fibrosis in chronic hepatitis C. Shaikh S, Memon MS, Ghani H, et al. J Coll Physicians Surg Pak. 2009 Aug;19(8):478-82

http://www.ncbi.nlm.nih.gov/pubmed/19651008?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Ethnicity and body mass Iindex are associated with hepatitis C presentation and progression. Kallwitz ER, Layden-Almer J, Dhamija M, et al. Clin Gastroenterol Hepatol. 2009 Aug 14. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Kallwitz%20ER%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Focal distribution of hepatitis C virus RNA in infected livers. Stiffler JD, Nguyen M, Sohn JA, Liu C, Kaplan D, Seeger C. 36: PLoS One. 2009 Aug 18;4(8):e6661.

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Stiffler%20JD%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Laparoscopic splenectomy with peginterferon and ribavirin therapy for patients with hepatitis C virus cirrhosis and hypersplenism. Akahoshi T, Tomikawa M, Korenaga D, et al. Surg Endosc. 2009 Aug 19. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/19690915?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Factors influencing long-term changes of mental health after interferon-alpha treatment of chronic hepatitis C. Schmidt F, Janssen G, Martin G, et al. Aliment Pharmacol Ther. 2009 Aug 18. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/19691667?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Efficacy and tolerability of rituximab with or without PEGylated interferon alfa-2b plus ribavirin in severe hepatitis C virus-related vasculitis: A long-term followup study of thirty-two patients. Terrier B, Saadoun D, Sène D, et al. Arthritis Rheum. 2009 Aug;60(8):2531-40.

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Terrier%20B%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Leukocyte interferon-alpha and ribavirin for treatment of chronic hepatitis C patients intolerant to pegylated-interferon. Adinolfi LE, Durante-Mangoni E, Salzillo M, et al. Intern Emerg Med. 2009 Aug 1. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Adinolfi%20LE%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

Basic and Applied Science, Pre-Clinical Studies

 

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

Dongliang Ge1, Jacques Fellay1, Alexander J. et al. Nature advance online publication 16 August 2009

http://www.nature.com/nature/journal/vaop/ncurrent/full/nature08309.html

 

Endotoxin receptor CD14 gene variants and histological features in chronic HCV infection.

Askar E, Ramadori G, Mihm S.  World J Gastroenterol. 2009 Aug 21;15(31):3884-90. 

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Askar%20E%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Modulations of cell cycle checkpoints in HCV associated disease. Sarfraz S, Hamid S, Ali S, Jafri W, Siddiqui A. BMC Infect Dis. 2009 Aug 10;9(1):125

http://www.ncbi.nlm.nih.gov/pubmed/19664251?ordinalpos=16&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Hepatic inflammation mediated by hepatitis C virus core protein is ameliorated by blocking complement activation. Chang ML, Yeh CT, Lin DY, Ho YP, Hsu CM, Bissell DM. BMC Med Genomics. 2009 Aug 8;2(1):51. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Chang%20ML%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Genetic variation in CLDN1 and susceptibility to hepatitis C virus infection. Bekker V, Chanock SJ, Yeager M, et al. J Viral Hepat. 2009 Aug 7. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Bekker%20V%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

HIV/HCV Coinfection

 

Treat early or wait and monitor? A qualitative analysis of provider hepatitis C virus treatment decision-making in the context of HIV coinfection. Wagner G, Ryan G, Osilla KC, Bhatti L, Goetz M, Witt M. AIDS Patient Care STDS. 2009 Aug 10. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/19663714?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Management of hepatitis C virus infection in HIV/HCV co-infected patients: clinical review. Singal AK, Anand BS. World J Gastroenterol. 2009 Aug 14;15(30):3713-24.       

http://www.ncbi.nlm.nih.gov/pubmed/19673011?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Determination of hepatitis C virus-infected, monocyte lineage reservoirs in individuals with or without HIV coinfection. Coquillard G, Patterson BK. J Infect Dis. 2009 Sep 15;200(6):947-54.

http://www.ncbi.nlm.nih.gov/pubmed/19678757

 

 

Occult hepatitis B virus infection in a cohort of HIV-positive patients: Correlation with hepatitis C virus coinfection, virological and immunological features. Morsica G, Ancarani F, Bagaglio S, et al. Infection. 2009 Aug 7. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Morsica%20G%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Longitudinal evaluation of viral interactions in treated HIV-hepatitis B co-infected patients with additional hepatitis C and D virus. Boyd A, Lacombe K, Miailhes P, et al. J Viral Hepat. 2009 Aug 4. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Boyd%20A%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Diagnosis of advanced fibrosis in HIV and hepatitis C virus-coinfected patients via a new noninvasive index: the HGM-3 index. Resino S, Micheloud D, Miralles P,et al. HIV Med. 2009 Aug 3. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Resino%20S%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Epidemiology, Diagnostics, and Miscellaneous Works

 

Quality of life considerations for patients with chronic hepatitis C. Foster GR. J Viral Hepat. 2009 Sep;16(9):605-11. Epub 2009 Aug 5.

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Foster%20GR%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Risk behaviors after hepatitis C virus seroconversion in young injection drug users in San Francisco. Tsui JI, Vittinghoff E, Hahn JA, Evans JL, Davidson PJ, Page K. Drug Alcohol Depend. 2009 Jul 30. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Tsui%20JI%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

The evolution of the major hepatitis C genotypes correlates with clinical response to interferon therapy. Pang PS, Planet PJ, Glenn JS. PLoS One. 2009 Aug 11;4(8):e6579. 

http://www.ncbi.nlm.nih.gov/pubmed/19668364?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Assessment and proposal of a new combination of screening criteria for hepatitis C in France. King LA, Le Strat Y, Meffre C, Delarocque-Astagneau E, Desenclos JC. Eur J Public Health. 2009 Aug 10. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/19667051?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Ultrasound surveillance for early detection of hepatocellular carcinoma among patients with chronic hepatitis C. Sato T, Tateishi R, Yoshida H, et al. Hepatol Int. 2009 Aug 6. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/19669240?ordinalpos=13&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

A methodology for successfully producing global translations of patient reported outcome measures for use in multiple Countries.  Two R, Verjee-Lorenz A, Clayson D, et al. Value Health. 2009 Aug 20. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Two%20R%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract

 

Prevalence of hepatitis C infection in New York City, 2004. Bornschlegel K, Berger M, Garg RK, et al. J Urban Health. 2009 Aug 12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Bornschlegel%20K%22%5BAuthor%5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_RVAbstract